Xgeva cost, Denosumab ( Injection Xgeva ) by Glaxo Smith Kline is a monoclonal antibody.
Xgeva is also used to increase bone mass in women and men with a high risk of bone fracture caused by receiving treatments for certain types of cancer.This may help to protect healthy cells from damage.
This medication guide provides information about the Prolia brand of denosumab. Xgeva is another brand of denosumab used to prevent bone fractures and other skeletal conditions in people with tumors that have spread to the bone.
You should not receive denosumab if you have low levels of calcium in your blood (hypocalcemia).
Prolia can harm an unborn baby or cause birth defects. Do not use if you are pregnant.
You should not receive Prolia if you are allergic to denosumab, or if you have low levels of calcium in your blood (hypocalcemia).
While you are using Prolia, you should not receive Xgeva, another brand of denosumab.
To make sure Prolia is safe for you, tell your doctor if you have:
kidney disease (or if you are on dialysis);
a weak immune system (caused by disease or by using certain medicines);
a history of hypoparathyroidism (decreased functioning of the parathyroid glands);
any condition that makes it hard for your body to absorb nutrients from food (malabsorption); or
if you are allergic to latex.
Denosumab may cause bone loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, gum infection, or slow healing after dental work.
Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids. Other risk factors include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem.
Denosumab can harm an unborn baby or cause birth defects. Do not use Prolia if you are pregnant.Tell your doctor right away if you become pregnant during treatment.